Role of bioactive substances in sheep's milk and its products in the prevention of neurodegenerative diseases

Aging is a major risk factor for cognitive decline, such as Alzheimer’s disease (AD). Sheep’s milk may play role in the prevention of neurodegenerative diseases because its high content functional peptides, lactoferrin. Lactoferrin can be used AD both an active therapeutic compound and drug nanocarrier. Compared to cow’s goat’s milks, sheep’s contains highest isomers conjugated linoleic acid (CLA). The c-9, t-11-CLA reduce pathological changes occurring mainly by reducing amount amyloid-β aggregates brain tissues. also higher concentrations vitamin D B-group vitamins, which have neuroprotective effects. This review summarizes current knowledge on products, with special focus diseases.